Genome Sequencing Identified a SARS-CoV-2 Lineage B.1.1.7 Strain with a High Number of Mutations from Dhaka, Bangladesh

Razib Mazumder; Ahmed Abdullah; Mohammad Enayet Hossain; M Mahfuzur Rahman; Omar Hamza Bin Manjur; Mustafizur Rahman; Dinesh Mondal

doi:10.1128/MRA.00345-21

Genome Sequencing Identified a SARS-CoV-2 Lineage B.1.1.7 Strain with a High Number of Mutations from Dhaka, Bangladesh

Microbiol Resour Announc. 2021 May 27;10(21):e0034521. doi: 10.1128/MRA.00345-21. Epub 2021 May 27.

Authors

Razib Mazumder¹, Ahmed Abdullah¹, Mohammad Enayet Hossain², M Mahfuzur Rahman², Omar Hamza Bin Manjur¹, Mustafizur Rahman², Dinesh Mondal¹

Affiliations

¹ Genomics Center, Laboratory Sciences and Services Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
² Virology Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

Abstract

We report a coding-complete genome sequence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain SARS-CoV-2/BGD/GC001, isolated from a Bangladeshi patient with respiratory symptoms. Phylogenetic analysis assigned this strain to lineage B.1.1.7, which presented a total of 36 mutations in the spike and other genomic regions compared to strain Wuhan Hu-1 (GenBank accession number NC_045512.2).