The Distribution Pattern of Traditional Chinese Medicine Syndromes in 549 Patients with Type 2 Diabetes

Diabetes Metab Syndr Obes. 2021 May 17:14:2209-2216. doi: 10.2147/DMSO.S295351. eCollection 2021.

Abstract

Objective: This study aimed to summarize the distribution pattern of traditional Chinese medicine (TCM) syndromes in patients with type 2 diabetes mellitus (T2DM).

Methods: The frequency, characteristics and distribution of all TCM syndromes of 549 patients with T2DM were analyzed.

Results: The average age of T2DM onset was higher in women than in men (ie, men experienced earlier onset). The distribution of TCM syndromes, in order of frequency, was as follows: damp-heat trapping spleen (including spleen deficiency and dampness, damp heat due to spleen deficiency, and qi weakness due to spleen deficiency) (58.29%), qi-yin deficiency (16.03%), deficiency of yin and excessive heat (12.93%), blood stasis in collaterals (9.41%), and yin-yang deficiency (3.21%). The physical intensity of patients' occupational activity was mainly light (49.6%), followed by heavy (31.4%) and moderate (19.0%).

Conclusion: Damp-heat trapping spleen is the most common TCM syndrome in patients with T2DM, with damp heat due to spleen deficiency the most significant subtype. This syndrome tends to occur in people over the age of 60 and those undertaking too much or too little physical activity in their occupational activities. The traditional "three more and one less" symptoms do not adequately describe the clinical symptoms of T2DM.

Keywords: TCM syndrome differentiation; clinical symptoms; damp heat due to spleen deficiency; epidemiology; type 2 diabetes.

Grants and funding

This study was funded by the Jiangxi Provincial Health and Family Planning Commission Chinese Medicine Research Project (2014A055). The funding body had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.