Hypoglossal schwannoma in the submandibular region

BMJ Case Rep. 2021 May 26;14(5):e242225. doi: 10.1136/bcr-2021-242225.

Abstract

Hypoglossal nerve schwannomas originating extracranially and mimicking a submandibular salivary gland tumour are extremely rare. A 55-year-old woman presented with a painless, gradually increasing swelling in the right submandibular region for the past 1 year. Fine-needle aspiration cytology and contrast-enhanced CT of the swelling showed features of submandibular gland malignant lesion. Intraoperatively, the right submandibular gland with a hypoglossal nerve swelling was noticed. Right submandibular gland along with the hypoglossal swelling were excised with adequate margins. However, the postoperative histopathology was reported as hypoglossal nerve schwannoma and a normal salivary gland. Accurate preoperative diagnosis of hypoglossal schwannomas may be challenging. A high level of suspicion must be sought for in cases with unusual clinical presentations and imaging characteristics. Herein, we report a rare presentation of submandibular hypoglossal schwannoma along with its clinical features and its management.

Keywords: ear; head and neck cancer; nose and throat/otolaryngology.

Publication types

  • Case Reports

MeSH terms

  • Cranial Nerve Neoplasms* / diagnostic imaging
  • Cranial Nerve Neoplasms* / surgery
  • Female
  • Humans
  • Hypoglossal Nerve Diseases* / diagnosis
  • Hypoglossal Nerve Diseases* / surgery
  • Middle Aged
  • Neurilemmoma* / diagnostic imaging
  • Neurilemmoma* / surgery
  • Submandibular Gland
  • Submandibular Gland Neoplasms*