Anti-mycobacterial Constituents from Medicinal Plants; A Review

Mini Rev Med Chem. 2021;21(19):3037-3051. doi: 10.2174/1389557521666210525120325.

Abstract

Effective treatment of tuberculosis has been hampered by the emergence of drug-resistant strains of Mycobacterium therapeutic facilities tuberculosis. With the global resurgence of tuberculosis with the development of multidrug-resistant cases, there is a call for the development of new drugs to combat these diseases. Throughout history, natural products have afforded a rich source of compounds that have found many applications in the fields of medicine, pharmacy and biology, and continued to play a significant role in the drug discovery and development process. This review article depicts the various potential plant extracts as well as plant derived phytoconstituents against the H37rv, the most persistent strains of Mycobacterium tuberculosis and its multidrug strains.

Keywords: Anti-mycobacterial.; H37rv; Mycobacterium tuberculosis; Tuberculosis; medicinal plants; phytoconstituents.

Publication types

  • Review

MeSH terms

  • Antitubercular Agents / pharmacology
  • Antitubercular Agents / therapeutic use
  • Microbial Sensitivity Tests
  • Mycobacterium tuberculosis*
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*
  • Tuberculosis* / drug therapy

Substances

  • Antitubercular Agents
  • Plant Extracts