Two new triterpenoid glycosides from leaves of Cyclocarya paliurus

Nat Prod Res. 2022 Oct;36(20):5277-5282. doi: 10.1080/14786419.2021.1931182. Epub 2021 May 25.

Abstract

Two dammarane glycosides (1-2) were isolated from the leaves of Cyclocarya paliurus. The structures of new compounds were established by application of spectroscopic methods, including one-dimensional and two-dimensional NMR, HRESIMS, and chemical hydrolysis. When evaluated against seven human cancer cell lines, the two compounds exhibited selective cytotoxicity to MCF-7 cells.[Formula: see text].

Keywords: Cyclocarya paliurus; cytotoxic activities; triterpenoid glycosides.

MeSH terms

  • Glycosides / chemistry
  • Humans
  • Juglandaceae* / chemistry
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry
  • Triterpenes* / chemistry

Substances

  • Glycosides
  • Plant Extracts
  • Triterpenes