Agallochin P, a new diterpene from Vietnamese mangrove Excoecaria agallocha L

Nat Prod Res. 2022 Oct;36(20):5283-5288. doi: 10.1080/14786419.2021.1931185. Epub 2021 May 25.

Abstract

A new diterpene (1) along with eight known compounds (2-9) were isolated from Excoecaria agallocha leaves. The structure and relative configuration of new compound were established on the basis of spectroscopic data analysis and confirmed by NMR chemical shifts calculation with DP4+ probability. Cytotoxicity of the isolated compounds were also evaluated.[Formula: see text].

Keywords: DP4+; Excoecaria agallocha; NMR calculation; diterpene; ent-kaurane.

MeSH terms

  • Diterpenes* / chemistry
  • Diterpenes* / pharmacology
  • Euphorbiaceae* / chemistry
  • Magnetic Resonance Spectroscopy

Substances

  • Diterpenes