Applications of bacteria and their derived biomaterials for repair and tissue regeneration

Regen Med. 2021 Jun;16(6):581-605. doi: 10.2217/rme-2020-0116. Epub 2021 May 25.

Abstract

Microorganisms such as bacteria and their derived biopolymers can be used in biomaterials and tissue regeneration. Various methods have been applied to regenerate damaged tissues, but using probiotics and biomaterials derived from bacteria with improved economic-production efficiency and highly applicable properties can be a new solution in tissue regeneration. Bacteria can synthesize numerous types of biopolymers. These biopolymers possess many desirable properties such as biocompatibility and biodegradability, making them good candidates for tissue regeneration. Here, we reviewed different types of bacterial-derived biopolymers and highlight their applications for tissue regeneration.

Keywords: 3D scaffolds; amyloid; bacterial proteins; bacterial-derived biopolymers; bacterial-derived collagen; bacterial-polysaccharides; microorganisms; probiotics; regenerative medicine; tissue regeneration.

Publication types

  • Review

MeSH terms

  • Bacteria
  • Biocompatible Materials*
  • Biopolymers
  • Tissue Engineering*
  • Tissue Scaffolds
  • Wound Healing

Substances

  • Biocompatible Materials
  • Biopolymers