Association of atrial fibrillation with outcomes in patients hospitalized with inflammatory bowel disease: an analysis of the National Inpatient Sample

Ebad Ur Rahman; Vijay Gayam; Pavani Garlapati; Neelkumar Patel; Fatima Farah; Adee El-Hamdani; Arfaat Khan; Paul I Okhumale; Wilbert S Aronow; Mehiar El-Hamdani

doi:10.5114/amsad.2021.105256

Association of atrial fibrillation with outcomes in patients hospitalized with inflammatory bowel disease: an analysis of the National Inpatient Sample

Arch Med Sci Atheroscler Dis. 2021 Apr 12:6:e40-e47. doi: 10.5114/amsad.2021.105256. eCollection 2021.

Authors

Affiliations

¹ Department of Internal Medicine, St Mary's Medical Center, Huntington, WV, USA.
² Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
³ Department of Internal Medicine, Deccan College of Medical Sciences, Hyderabad, India.
⁴ Alleghany Health Network, Pittsburg, PA, USA.
⁵ Department of Cardiology, Henry Ford Hospital, Detroi, MI, USA.
⁶ Department of Cardiology, Marshall University, Huntington, WV, USA.
⁷ Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY, USA.

Abstract

Introduction: We aimed to determine in-hospital outcomes, length of hospital stay (LOS) and resource utilization in a contemporary cohort of patients with inflammatory bowel disease (IBD) and atrial fibrillation (AFIB).

Material and methods: The National Inpatient Sample database October 2015 to December 2017 was utilized for data analysis using the International Classification of Diseases, Tenth Revision codes to identify the patients with the principal diagnosis of IBD.

Results: Of 714,863 IBD patients, 64,599 had a diagnosis of both IBD and AFIB. We found that IBD patients with AFIB had a greater incidence of in-hospital mortality (OR = 1.3; 95% CI: 1.1-1.4), sepsis (OR = 1.2; 95% CI: 1.1-1.3), mechanical ventilation (OR = 1.2; 95% CI: 1.1-1.5), shock requiring vasopressor (OR = 1.4; 95% CI: 1.1-1.9), lower gastrointestinal bleeding (LGIB) (OR = 1.09, 95% CI: 1.04-1.1), and hemorrhage requiring blood transfusion (OR = 1.2, 95% CI: 1.17-1.37). Mean LOS ± SD, mean total charges and total costs were higher in patients with IBD and AFIB.

Conclusions: In this study, IBD with AFIB was associated with increased in-hospital mortality and morbidity, mean LOS and resource utilization.

Keywords: NIS; atrial fibrillation; inflammatory bowel disease; outcomes; propensity-matched.