A longitudinal case series of IM ketamine for patients with severe and enduring eating disorders and comorbid treatment-resistant depression

Terry Schwartz; Mary Ellen Trunko; David Feifel; Emily Lopez; Danika Peterson; Guido K W Frank; Walter Kaye

doi:10.1002/ccr3.3869

A longitudinal case series of IM ketamine for patients with severe and enduring eating disorders and comorbid treatment-resistant depression

Clin Case Rep. 2021 Apr 4;9(5):e03869. doi: 10.1002/ccr3.3869. eCollection 2021 May.

Authors

Terry Schwartz¹, Mary Ellen Trunko¹, David Feifel¹, Emily Lopez¹, Danika Peterson¹, Guido K W Frank¹, Walter Kaye¹

Affiliation

¹ Department of Psychiatry University of California San Diego San Diego CA USA.

Abstract

Severe and enduring eating disorders (EDs) have the highest mortality rate of all psychiatric illnesses (Arch Gen Psychiatry, 2011, 68, 724), especially when comorbid with treatment-resistant depression (TRD) (Psychiatr Res, 2016, 244, 45). We report on four patients with enduring EDs and TRD treated with repeat ketamine over 12 + months, showing improvement in depression with only modest changes in ED symptoms.

Keywords: depression; eating disorders; ketamine; treatment.

Publication types

Case Reports