Infectious Gastroenteritis in Transplant Patients

Lemuel R Non; Dilek Ince

doi:10.1016/j.gtc.2021.02.013

Infectious Gastroenteritis in Transplant Patients

Gastroenterol Clin North Am. 2021 Jun;50(2):415-430. doi: 10.1016/j.gtc.2021.02.013. Epub 2021 Apr 23.

Authors

Lemuel R Non¹, Dilek Ince²

Affiliations

¹ Department of Internal Medicine, University of Iowa, Carver College of Medicine, GH SW34, 200 Hawkins Drive, Iowa City, IA 52242, USA.
² Department of Internal Medicine, University of Iowa, Carver College of Medicine, GH SE418, 200 Hawkins Drive, Iowa City, IA 52242, USA. Electronic address: dilek-ince@uiowa.edu.

PMID: 34024449
DOI: 10.1016/j.gtc.2021.02.013

Abstract

Infectious gastroenteritis is common after transplantation and can lead to increased morbidity and mortality. A wide range of organisms can lead to gastroenteritis in this patient population. Clostridioides difficile, cytomegalovirus, and norovirus are the most common pathogens. Newer diagnostic methods, especially multiplex polymerase chain reaction, have increased the diagnostic yield of infectious etiologies. In this review, we describe the epidemiology and risk factors for common infectious pathogens leading to gastroenteritis.

Keywords: Diagnostic workup; Gastrointestinal infection; Hematopoietic stem cell transplantation; Solid organ transplantation.

Publication types

Review

MeSH terms

Diarrhea
Gastroenteritis* / diagnosis
Gastroenteritis* / epidemiology
Gastroenteritis* / etiology
Hematopoietic Stem Cell Transplantation*
Humans
Norovirus* / genetics
Organ Transplantation* / adverse effects