Postinfectious Neurologic Complications in COVID-19: A Complex Case Report

J Nucl Med. 2021 Aug 1;62(8):1171-1176. doi: 10.2967/jnumed.120.256099. Epub 2021 May 20.

Abstract

A 40-y-old woman with severe acute respiratory syndrome coronavirus 2 infection developed neurologic manifestations (confusion, agitation, seizures, dyskinesias, and parkinsonism) a few weeks after the onset of severe acute respiratory syndrome. MRI and cerebrospinal fluid analyses were unremarkable, but 18F-FDG PET/CT showed limbic and extralimbic hypermetabolism. A full recovery, alongside 18F-FDG normalization in previously hypermetabolic areas, was observed after intravenous immunoglobulin administration.

Keywords: COVID-19; IVIg; PET; SARS-CoV-2; encephalitis; neuroimaging.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / diagnostic imaging
  • Brain Diseases / etiology*
  • COVID-19 / complications*
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • SARS-CoV-2*

Substances

  • Fluorodeoxyglucose F18