Temperament, character and decision-making characteristics of patients with major depressive disorder following a suicide attempt

PLoS One. 2021 May 20;16(5):e0251935. doi: 10.1371/journal.pone.0251935. eCollection 2021.

Abstract

Background: Multiple psychological factors of suicidal behaviour have been identified so far; however, little is known about state-dependent alterations and the interplay of the most prominent components in a suicidal crisis. Thus, the combined effect of particular personality characteristics and decision-making performance was observed within individuals who recently attempted suicide during a major depressive episode.

Methods: Fifty-nine medication-free major depressed patients with a recent suicide attempt (within 72 h) and forty-five healthy control individuals were enrolled in this cross-sectional study. Temperament and character factors, impulsivity and decision-making performance were assessed. Statistical analyses aimed to explore between-group differences and the most powerful contributors to suicidal behaviour during a depressive episode.

Results: Decision-making and personality differences (i.e. impulsivity, harm avoidance, self-directedness, cooperativeness and transcendence) were observed between the patient and the control group. Among these variables, decision-making, harm avoidance and self-directedness were shown to have the strongest impact on a recent suicide attempt of individuals with a diagnosis of major depressive disorder according to the results of the binary logistic regression analysis. The model was significant, adequately fitted the data and correctly classified 79.8% of the cases.

Conclusions: The relevance of deficient decision-making, high harm avoidance and low self-directedness was modelled in the case of major depressed participants with a recent suicide attempt; meaning that these individuals can be described with the myopia for future consequences, a pessimistic, anxious temperament; and a character component resulting in the experience of aimlessness and helplessness. Further studies that use a within-subject design should identify and confirm additional characteristics specific to the suicidal mind.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety / physiopathology
  • Anxiety / prevention & control
  • Anxiety / psychology
  • Anxiety / therapy*
  • Clinical Decision-Making
  • Depressive Disorder, Major / physiopathology
  • Depressive Disorder, Major / prevention & control
  • Depressive Disorder, Major / psychology
  • Depressive Disorder, Major / therapy*
  • Emotions / physiology
  • Female
  • Humans
  • Impulsive Behavior / physiology
  • Male
  • Middle Aged
  • Personality Disorders / physiopathology
  • Personality Disorders / therapy*
  • Suicide, Attempted / prevention & control*
  • Suicide, Attempted / psychology

Associated data

  • figshare/10.6084/m9.figshare.13317515

Grants and funding

The publication is supported by the University of Szeged Open Access Fund (Grant Number: 5099). The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.