Akinetic mutism in COVID-19-related encephalopathy: A cytokine-mediated maladaptive sickness behavioral response?

Umberto Pensato; Lorenzo Muccioli; Damir Janigro; Maria Guarino; Francesca Bisulli; Pietro Cortelli

doi:10.1016/j.bbih.2021.100272

Akinetic mutism in COVID-19-related encephalopathy: A cytokine-mediated maladaptive sickness behavioral response?

Brain Behav Immun Health. 2021 Aug:15:100272. doi: 10.1016/j.bbih.2021.100272. Epub 2021 May 13.

Authors

Umberto Pensato¹, Lorenzo Muccioli¹, Damir Janigro², Maria Guarino³, Francesca Bisulli^{1

3}, Pietro Cortelli^{1

3}

Affiliations

¹ Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.
² Department of Physiology, Case Western Reserve University, Cleveland, OH, United States.
³ IRCCS Istituto delle Scienze Neurologiche di Bologna, Full Member of the ERN-EpiCARE network, Bologna, Italy.

No abstract available

Keywords: Autonomic nervous system; CAR T-cells; Cytokine storm-associated encephalopathy (CySE); Cytokine-mediated neuroinflammation; Delirium; Frontal lobe; Hypothalamus; ICANS; Neuroinflammation; Sepsis.

Publication types

Review