Encapsulation of water soluble pesticides for extended delivery of pesticides without contaminating water bodies

J Environ Sci Health B. 2021;56(5):458-466. doi: 10.1080/03601234.2021.1908798. Epub 2021 May 17.

Abstract

The main objective of this study is to develop polymeric encapsulated formulation for the water soluble broad-spectrum pesticides. Pesticides contaminate the environment in different ways but foremost hazards are linked with the contamination of water bodies. Water soluble pesticides are the major deleterious agents and go off into ground water and different water bodies through leaching or surface runoff from the applied places. Besides this some of the water soluble pesticides are broad-spectrum, but proper methods and techniques are not available for their effective and safe usage, all broad-spectrum pesticide are disappearing from the pesticide lists every year. Hence, the present study is based on development of encapsulated formulation for water soluble broad-spectrum pesticide i.e. Monocrotophos. In this study, water soluble pesticide was encapsulated in polyvinyl alcohol (PVA) polymer along with surfactants and cross linker. The developed microspheres were analyzed in HPLC for calculating loading capacity and encapsulation efficacy, these were calculated 0.75 and 90% respectively. The FT-IR data results confirmed that the monocrotophos successfully encapsulated in the PVA polymer with respective bands. The degradation studies show that in encapsulated formulation monocrotophos degradation was found only 10% after 94 hrs. Optical micrographs in aqeous solution indicate spherical shapes with size in the rage of 7-8 µm of encapsulated formulation. XRD data further crystalline nature of polymeric encapsulated formulation. The study may provide a new corridor to save the broad-spectrum water soluble pesticides which are on the verge to be banned.

Keywords: Water soluble pesticides; broad-spectrum; encapsulation; monocrotophos; water contamination.

MeSH terms

  • Delayed-Action Preparations
  • Drug Compounding
  • Drug Delivery Systems / methods*
  • Microspheres
  • Monocrotophos / chemistry
  • Pesticides / chemistry*
  • Polyvinyl Alcohol / chemistry
  • Surface-Active Agents / chemistry
  • Water Pollutants, Chemical / chemistry*

Substances

  • Delayed-Action Preparations
  • Pesticides
  • Surface-Active Agents
  • Water Pollutants, Chemical
  • Monocrotophos
  • Polyvinyl Alcohol