Different Parts of the Chicken Embryo Egg Improve D-Galactose-Induced Aging in a Mice Model

Biomed Res Int. 2021 Apr 27:2021:6654683. doi: 10.1155/2021/6654683. eCollection 2021.

Abstract

Chick (CE) or duck embryo eggs are known for nutritional supplement foods in traditional East countries for physical fitness enhancement and postpartum conditioning for many years. In this study, we evaluated the effects of different parts of the 10-day CE (embryo: CEr, yolk: CEw, and chorioallantoic membrane: CEp) on the antifatigue and antiaging activities in a D-galactose- (D-gal) induced aging mice model. The results showed CEp obviously increased the muscle weight and the liver and muscle glycogen content and enhanced exercise performance. In the antiaging assay, CEp significantly increased the activity of superoxide dismutase (SOD) and Glutathione Peroxidase (GPx). Moreover, the immunohistochemistry results of NRF-2 and HO-1 were also detected in the livers of mice in the D-gal/CEp group. The only partially potential such as CEr might improve OFT function with TG level, and CEw had strange grip strength. Therefore, we suggest that CEp has a potent antifatigue ability and could minimize the occurrence of age-associated disorders, more than other parts of the 10 days chicken embryo egg.

MeSH terms

  • Aging / drug effects*
  • Animals
  • Biological Products / pharmacology*
  • Chick Embryo*
  • Chorioallantoic Membrane / chemistry
  • Dietary Supplements*
  • Egg Yolk / chemistry
  • Galactose / adverse effects
  • Hand Strength
  • Liver / chemistry
  • Liver / drug effects
  • Male
  • Medicine, Chinese Traditional
  • Mice
  • Mice, Inbred C57BL
  • Muscle Strength / drug effects
  • Muscles / drug effects
  • Muscles / metabolism
  • Superoxide Dismutase / metabolism

Substances

  • Biological Products
  • Superoxide Dismutase
  • Galactose