Bronchiectasis-Could Immunonutrition Have a Role to Play in Future Management?

Front Nutr. 2021 Apr 29:8:652410. doi: 10.3389/fnut.2021.652410. eCollection 2021.

Abstract

Bronchiectasis is a chronic condition in which areas of the bronchial tubes become permanently widened predisposing the lungs to infection. Bronchiectasis is an age-associated disease with the highest prevalence in people older than 75 years. While the prevalence of bronchiectasis is higher in males, disease is more severe in females who have a poorer prognosis. The overall prevalence of the disease is thought to be rising. Its aetiology is multi-faceted, but a compromised immune system is now thought to play a central role in the pathology of this disease. Research has begun to study the role of malnutrition and certain nutrients-vitamin D and zinc-along with the role of the lung microbiome in relation to the management of bronchiectasis. Given this, the present mini review sets out to provide an overview of the state-of-the-art within the field, identify research gaps and pave the way for future developments and research investment within this field.

Keywords: bronchiectasis; immunonutrition; inflammation; lung health; respiratory tract infections.

Publication types

  • Review