1 Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK; National Institute for Health Research (NIHR), Oxford Biomedical Research Centre, Oxford, UK; School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.
2 Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK; National Institute for Health Research (NIHR), Oxford Biomedical Research Centre, Oxford, UK. Electronic address: mona.bafadhel@ndm.ox.ac.uk.