Quality control of protein reagents for the improvement of research data reproducibility

Nat Commun. 2021 May 14;12(1):2795. doi: 10.1038/s41467-021-23167-z.

Abstract

Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents should provide more reliable experimental data.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Humans
  • Indicators and Reagents / analysis
  • Indicators and Reagents / chemistry
  • Indicators and Reagents / standards*
  • Proteins / analysis
  • Proteins / chemistry
  • Proteins / standards*
  • Quality Control
  • Reproducibility of Results

Substances

  • Indicators and Reagents
  • Proteins