Clinical Databases for Breast Cancer Research

Adv Exp Med Biol. 2021:1187:493-509. doi: 10.1007/978-981-32-9620-6_26.

Abstract

Clinical database is a collection of clinical data related to patients, which can be used for analysis and research. Clinical data can be classified into several categories: patient-related, tumor-related, diagnostics-related, treatment-related, outcome-related, administration-related, and other clinical data. Clinical databases can be classified according to the data types of clinical databases, ranges of institutes, and accessibility to data. The numbers of papers and clinical trials are rapidly increasing. Recently, more than 9000 papers related to breast cancer have been published annually, and more than 7000 papers related to human breast cancer are published annually. The speed of increase is expected to be faster and faster in future. Now, almost 8000 clinical trials are registered world widely. Main research areas of breast cancer can be classified into followings; epidemiology, screening and prevention, diagnosis, treatment, and prognosis. Clinical databases that are available for breast cancer research are also introduced in this chapter. The analysis of big data is expected to be the mainstream of breast cancer research using clinical databases. As the technology of artificial intelligence (AI) is rapidly evolving, the technology of deep learning starts to be applied for breast cancer research. In near future, AI technology is predicted to penetrate deeply the field of breast cancer research.

Keywords: Artificial intelligence; Big data; Breast cancer; Breast cancer research; Clinical data; Clinical database.

MeSH terms

  • Artificial Intelligence*
  • Big Data
  • Breast
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / epidemiology
  • Breast Neoplasms* / therapy
  • Databases, Factual
  • Humans