BACE1: from biomarker to Alzheimer's disease therapeutical target

Aging (Albany NY). 2021 May 11;13(9):12299-12300. doi: 10.18632/aging.203064. Epub 2021 May 11.

Authors

Carlo Cervellati¹, Giuseppe Valacchi^{2

3

4}, Giovanni Zuliani¹

Affiliations

¹ Department of Translational Medicine and for Romagna, University of Ferrara, Ferrara, 44121, Italy.
² Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, 44121, Italy.
³ Plants for Human Health Institute, Animal Science Department, NC State University, Kannapolis, NC, 28081, USA.
⁴ Department of Food and Nutrition, Kyung Hee University, Seoul, South Korea.

No abstract available

Keywords: Alzheimer’s disease; BACE1; amyloid- β; blood-based biomarkers.

Publication types

Review

MeSH terms

Alzheimer Disease / metabolism*
Alzheimer Disease / therapy*
Amyloid Precursor Protein Secretases / metabolism*
Amyloid beta-Peptides / metabolism
Amyloid beta-Protein Precursor / metabolism
Animals
Aspartic Acid Endopeptidases / metabolism*
Biomarkers / analysis*
Humans

Substances

Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Biomarkers
Amyloid Precursor Protein Secretases
Aspartic Acid Endopeptidases
BACE1 protein, human