Automatic extraction of the mitral valve chordae geometry for biomechanical simulation

Int J Comput Assist Radiol Surg. 2021 May;16(5):709-720. doi: 10.1007/s11548-021-02368-3. Epub 2021 May 12.

Abstract

Purpose: Mitral valve computational models are widely studied in the literature. They can be used for preoperative planning or anatomical understanding. Manual extraction of the valve geometry on medical images is tedious and requires special training, while automatic segmentation is still an open problem.

Methods: We propose here a fully automatic pipeline to extract the valve chordae architecture compatible with a computational model. First, an initial segmentation is obtained by sub-mesh topology analysis and RANSAC-like model-fitting procedure. Then, the chordal structure is optimized with respect to objective functions based on mechanical, anatomical, and image-based considerations.

Results: The approach has been validated on 5 micro-CT scans with a graph-based metric and has shown an [Formula: see text] accuracy rate. The method has also been tested within a structural simulation of the mitral valve closed state.

Conclusion: Our results show that the chordae architecture resulting from our algorithm can give results similar to experienced users while providing an equivalent biomechanical simulation.

Keywords: Biomechanical simulation; Graph-based validation; Image-based modeling; Mitral valve.

MeSH terms

  • Algorithms
  • Animals
  • Biomechanical Phenomena
  • Computer Simulation
  • Image Processing, Computer-Assisted
  • Mitral Valve / anatomy & histology*
  • Mitral Valve / diagnostic imaging*
  • Mitral Valve Insufficiency / diagnostic imaging*
  • Mitral Valve Insufficiency / physiopathology*
  • Mitral Valve Insufficiency / surgery
  • Models, Anatomic
  • Pattern Recognition, Automated
  • Reproducibility of Results
  • Swine
  • X-Ray Microtomography