Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses

Signal Transduct Target Ther. 2021 May 10;6(1):182. doi: 10.1038/s41392-021-00608-1.

Siyuan Su^#^{1

2}, Jianfeng Chen^#^{1

2}, Ying Wang^#^{1

2}, Lilly M Wong³, Zhichuan Zhu^{1

2}, Guochun Jiang^{2

3}, Pengda Liu^{4

5}

¹ Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
² Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
³ UNC HIV Cure Center, Institute of Global Health and Infectious Diseases, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
⁴ Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. pengda_liu@med.unc.edu.
⁵ Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. pengda_liu@med.unc.edu.

^# Contributed equally.

No abstract available

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