Achievement in active agent structures as a power tools in tumor angiogenesis imaging

Biochim Biophys Acta Rev Cancer. 2021 Aug;1876(1):188560. doi: 10.1016/j.bbcan.2021.188560. Epub 2021 May 10.

Abstract

According to World Health Organization (WHO) cancer is the second most important cause of death globally. Because angiogenesis is considered as an essential process of growth, proliferation and tumor progression, within this review we decided to shade light on recent development of chemical compounds which play a significant role in its imaging and monitoring. Indeed, the review gives insight about the current achievements of active agents structures involved in imaging techniques such as: positron emission computed tomography (PET), magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT), as well as combination PET/MRI and PET/CT. The review aims to provide the journal audience with a comprehensive and in-deep understanding of chemistry policy in tumor angiogenesis imaging.

Keywords: Contrast agent; Imaging; MRI; PET; SPECT; Tracer; Tumor angiogenesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Animals
  • Contrast Media*
  • Humans
  • Magnetic Resonance Imaging*
  • Neoplasms / blood supply*
  • Neoplasms / diagnostic imaging*
  • Neoplasms / drug therapy
  • Neovascularization, Pathologic*
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography*
  • Predictive Value of Tests
  • Radiopharmaceuticals*
  • Tomography, Emission-Computed, Single-Photon

Substances

  • Angiogenesis Inhibitors
  • Contrast Media
  • Radiopharmaceuticals