Kinetic model of polyunsaturated fatty acids oxidation in micelles

E M Pliss; M E Soloviev; D V Loshadkin; S V Molodochkina; O T Kasaikina

doi:10.1016/j.chemphyslip.2021.105089

Kinetic model of polyunsaturated fatty acids oxidation in micelles

Chem Phys Lipids. 2021 Jul:237:105089. doi: 10.1016/j.chemphyslip.2021.105089. Epub 2021 May 10.

Authors

E M Pliss¹, M E Soloviev², D V Loshadkin², S V Molodochkina³, O T Kasaikina⁴

Affiliations

¹ P.G. Demidov Yaroslavl State University, Russian Federation. Electronic address: pliss@uniyar.ac.ru.
² Yaroslavl State Technical University, Russian Federation.
³ P.G. Demidov Yaroslavl State University, Russian Federation.
⁴ N.N. Semenov Federal Research Center for Chemical Physics Russian Academy of Sciences, Russian Federation.

PMID: 33965418
DOI: 10.1016/j.chemphyslip.2021.105089

Abstract

A kinetic model of polyunsaturated fatty acids (PUFAs) radical chain oxidation in micelles is presented, taking into account the diffusion of active intermediates between aqueous and organic phases, and its effect on the detailed mechanism of the process. The model made it possible to indirectly involve the structural changes of micelles and their kinetic characteristics by varying the actual values of the reactions rate constants. The modeling results are in good agreement with experimental data for the oxidation of methyl linoleate and linoleic acid.

Keywords: Kinetic modeling; Micelles; Oxidation of PUFAs; Radical intermediates.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fatty Acids, Unsaturated / chemistry*
Kinetics
Linoleic Acid / chemistry
Micelles*
Models, Chemical*
Octoxynol / chemistry
Oxidation-Reduction

Substances

Fatty Acids, Unsaturated
Micelles
Octoxynol
Linoleic Acid