The effect of TGFβRI inhibition on extracellular matrix structure and stiffness in hypertrophic scar-specific fibroblast-derived matrix models

Biochem Biophys Res Commun. 2021 Jun 25:559:245-251. doi: 10.1016/j.bbrc.2021.04.071. Epub 2021 May 5.

¹ Department of Dermatology, Leiden University Medical Centre, 2333 ZA, Leiden, the Netherlands. Electronic address: rs.raktoe@gmail.com.
² LaserLaB Amsterdam, Department of Physics and Astronomy, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV, Amsterdam, the Netherlands; Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, P.O. Box 1074, 1940 EB, Beverwijk, the Netherlands; Amsterdam UMC Location VUmc, Department of Plastic, Reconstructive and Hand Surgery, Amsterdam Movement Sciences, PO Box 7057, 1007 MB, Amsterdam, the Netherlands.
³ LaserLaB Amsterdam, Department of Physics and Astronomy, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV, Amsterdam, the Netherlands.
⁴ Department of Dermatology, Leiden University Medical Centre, 2333 ZA, Leiden, the Netherlands.
⁵ Burn Center and Department of Plastic and Reconstructive Surgery, Red Cross Hospital, P.O. Box 1074, 1940 EB, Beverwijk, the Netherlands; Amsterdam UMC Location VUmc, Department of Plastic, Reconstructive and Hand Surgery, Amsterdam Movement Sciences, PO Box 7057, 1007 MB, Amsterdam, the Netherlands.

No abstract available

Keywords: Burn wounds; Dynamic indentation; Exon skipping; Extracellular matrix; Second harmonic generation.

Publication types