Human-monkey chimeras: Monkey see, monkey do

Victoria L Mascetti; Roger A Pedersen

doi:10.1016/j.stem.2021.04.025

Human-monkey chimeras: Monkey see, monkey do

Cell Stem Cell. 2021 May 6;28(5):787-789. doi: 10.1016/j.stem.2021.04.025.

Authors

Victoria L Mascetti¹, Roger A Pedersen²

Affiliations

¹ Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford University, CA 94305, USA. Electronic address: mascetti@stanford.edu.
² Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford University, CA 94305, USA.

PMID: 33961759
DOI: 10.1016/j.stem.2021.04.025

Abstract

Recently in Cell, Tan et al. (2021) report the successful generation of human-monkey chimeras in vitro, providing an opportunity for new insights into the biology of human stem cells and early human development in an embryonic environment that is evolutionary closer to human than previously studied rodent and domestic species.

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MeSH terms

Animals
Chimera*
Haplorhini
Humans
Pluripotent Stem Cells*