Associations between Serum Vitamins and Serum Uric Acid in a Population of Shenyang, China

J Nutr Sci Vitaminol (Tokyo). 2021;67(2):77-83. doi: 10.3177/jnsv.67.77.

Abstract

Previous studies have demonstrated that serum vitamins are associated with serum uric acid (SUA) level. However, no study has comprehensively investigated whether various serum vitamins are associated with SUA level in a general population. Thus, a cross-sectional study was designed to explore the associations between SUA level and serum vitamins. The data of this study for SUA levels were collected from participants aged ≥18 y. Serum vitamin and other baseline information, including age and body mass index, was determined. Moreover, associations between SUA level and serum vitamins were explored using analysis of covariance. Higher levels of SUA were significantly associated with a higher level of serum vitamins A, B9 and B5 (p<0.05). Higher level of SUA were associated with a lower level of serum vitamins C, and D2 (p<0.05). No significant associations were found between vitamins C, and D2 and SUA levels after adjustment. Study results suggested that serum vitamins A, B9 and B5 were positively associated, whereas serum vitamins C, and D2 were inversely associated with SUA levels.

Keywords: Chinese population; comprehensively investigation; cross-sectional study; serum uric acid; serum vitamins.

MeSH terms

  • Body Mass Index
  • China
  • Cross-Sectional Studies
  • Humans
  • Risk Factors
  • Uric Acid*
  • Vitamins*

Substances

  • Vitamins
  • Uric Acid