A novel nonenzymatic ascorbic acid electrochemical sensor based on gold nanoparticals-chicken egg white-copper phosphate-graphene oxide hybrid nanoflowers

Jiaojiao Gao; Hui Liu; Kexin Wu; Jifeng Yan; Cheng Tong

doi:10.1088/1361-6528/abfe28

A novel nonenzymatic ascorbic acid electrochemical sensor based on gold nanoparticals-chicken egg white-copper phosphate-graphene oxide hybrid nanoflowers

Nanotechnology. 2021 May 21;32(32). doi: 10.1088/1361-6528/abfe28.

Authors

Jiaojiao Gao^{1

2}, Hui Liu¹, Kexin Wu¹, Jifeng Yan¹, Cheng Tong¹

Affiliations

¹ School of Materials Science and Engineering, Shaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic Materials, Shaanxi University of Science and Technology, Xi'an 710021, People's Republic of China.
² College of Chemistry and Chemical Engineering, Yan'an University, Yan'an 716000, People's Republic of China.

PMID: 33951620
DOI: 10.1088/1361-6528/abfe28

Abstract

Au-CEW-Cu₃(PO₄)₂-GO nanoflowers (HNFs), which were assembled of gold nanoparticals (Au NPs), chicken egg white (CEW), copper phosphate (Cu₃(PO₄)₂) and graphene oxide (GO) together to form a flower-like organic/inorganic hybrid nanocomposite, were synthesized through a simple and gentle one-pot co-precipitation method. The prepared samples were well characterized by scanning electron microscope, transmission electron microscope, energy dispersive x-ray spectrometer, x-ray diffraction and Raman spectrometer. The prepared Au-CEW-Cu₃(PO₄)₂-GO HNFs was used to modify glassy carbon electrode to fabricate an electrochemical sensor for detection of ascorbic acid (AA). The electrochemical test results show that the linear range of the developed sensor is 8-300μM and the detection limit is 2.67μM (S/N = 3). While this sensor displays high sensitivity of 6.01 × 10^-3μAμM^-1cm^-2and low detection potential of 35 mV due to the combination of the high conductivity of Au NPs, the larger specific surface area of GO and the intrinsic electrocatalytic activity of CEW-Cu₃(PO₄)₂HNFs. Moreover, the Au-CEW-Cu₃(PO₄)₂-GO HNFs-based sensor was successfully developed for application in electrochemical detection of AA in vitamin C tablets.

Keywords: ascorbic acid; chicken egg white-Cu3(PO4)2 nanoflowers; colloidal gold nanoparticles; electrochemical sensors; graphene oxide; organic/inorganic hybrid nanocomposite.