The Role of 99mTc-antigranulocyte SPECT/CT In Community-Acquired Diabetic Foot Osteomyelitis: A Clinical Experience

Curr Diabetes Rev. 2022;18(6):e030521193111. doi: 10.2174/1573399817666210503140303.

Abstract

Background: Magnetic resonance imaging (MRI) is the actual gold standard for the radiological diagnosis of diabetic foot osteomyelitis (DFO).

Materials and methods: MRI is not always available and many patients have contraindications. We evaluated the clinical value of 99mTc-antigranulocyte SPECT/CT (AGS) in eight DFO patients who underwent MRI before.

Results: The goal was to have a better clinical view on the extent of bone infection and to ameliorate the surgical approach for DFO. However, this additional scintigraphy did not change anything in the clinical approach.

Conclusion: We shared our experience with AGS for clinical management of complex DFO cases.

Keywords: Anti-granulocyte SPECT/CT; clinical benefit; comparisons; diabetic foot; magnetic resonance imaging; osteomyelitis.

MeSH terms

  • Diabetes Mellitus*
  • Diabetic Foot* / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging
  • Osteomyelitis* / diagnostic imaging
  • Osteomyelitis* / etiology
  • Radionuclide Imaging
  • Sensitivity and Specificity
  • Tomography, Emission-Computed, Single-Photon
  • Tomography, X-Ray Computed