Rapid and low-cost amplicon visualization for nucleic acid amplification tests using magnetic microbeads

Analyst. 2021 May 4;146(9):2818-2824. doi: 10.1039/d0an02349c.

Abstract

This study presents a rapid and low-cost amplicon detection method in which amplicons are attached to magnetic microbeads, suspended in deionized water, and subjected to a magnetic field on a hydrophilic surface resulting in the circular agglomeration of amplicon-conjugated microbeads, visible to the naked eye.

MeSH terms

  • Magnetic Phenomena
  • Magnetics*
  • Microspheres
  • Nucleic Acid Amplification Techniques*