Terragines F-G produced by endophytic Bacillus sp. SH-1.2-ROOT-18 from Dendrobium officinale

Nat Prod Res. 2022 Oct;36(19):5058-5063. doi: 10.1080/14786419.2021.1914614. Epub 2021 May 5.

Abstract

Two new terragine analogs (12) with special succinimide and aminopentane moieties were isolated from the fermentation broth of Bacillus sp. SH-1.2-ROOT-18, an endophyte previously discovered from the root of Dendrobium officinale. The structures were elucidated base on comprehensive 1 D/2D NMR and MS data analysis. Complete NMR assignments for the first reported naturally occurring metabolite 3 was also provided.[Formula: see text].

Keywords: Bacillus sp; Dendrobium officinale; Terragine; endophyte; natural product.

MeSH terms

  • Bacillus*
  • Dendrobium* / chemistry
  • Endophytes / chemistry
  • Fermentation
  • Succinimides

Substances

  • Succinimides