Prevalence of comorbidities in multiple sclerosis patients with neurogenic bladder

A Declemy; R Haddad; C Chesnel; A Charlanes; F Le Breton; S Sheikh Ismael; G Amarenco

doi:10.1016/j.purol.2020.10.011

Prevalence of comorbidities in multiple sclerosis patients with neurogenic bladder

Prog Urol. 2021 Oct;31(12):732-738. doi: 10.1016/j.purol.2020.10.011. Epub 2021 Apr 30.

Authors

A Declemy¹, R Haddad², C Chesnel², A Charlanes², F Le Breton², S Sheikh Ismael², G Amarenco²

Affiliations

¹ GREEN GRC-01 UPMC (Group of clinical REsEarch in Neuro-urology), Sorbonne University, Paris, France; Department of Neuro-urology, Tenon Hospital, APHP, Paris, France. Electronic address: declemy.a@chu-nice.fr.
² GREEN GRC-01 UPMC (Group of clinical REsEarch in Neuro-urology), Sorbonne University, Paris, France; Department of Neuro-urology, Tenon Hospital, APHP, Paris, France.

PMID: 33941463
DOI: 10.1016/j.purol.2020.10.011

Abstract

Aims: The aim of this study was to define the prevalence of comorbidities among multiple sclerosis patients with lower urinary tract symptoms.

Methods: A retrospective study of data collected prospectively from January 2000 to March 2016 was carried out using a database. Comorbidities were divided into several classes according to the International Classification of Diseases (ICD-10).

Results: One hundred and fifty-five patients were included. All had a neurogenic bladder with 150 (96%) overactive bladder. EDSS score was≥6 in 44 patients (28%). Comorbidities were present in 79 (50,9%) and the most frequent ones were cardiovascular (14,2%), endocrinological (10,3%), urological (8,4%), abdominal (7,7%). Overweight (BMI≥25) was observed in 63 (40%). A strict relationship was found for BMI and stress urinary incontinence (P<0.001) as well as voiding dysfunction (P=0.003) without significant association for BMI and overactive bladder.

Conclusion: Prevalence of comorbidities is important in MS (more than 50%). A significant association is found between overweight, stress urinary incontinence and voiding dysfunction. Knowledge of these comorbidities in MS is important since the presence of these urinary symptoms not related to neurogenic bladder must lead to a specific treatment.

Level of evidence: 3.

Keywords: Bladder; Comorbidities; Comorbidités; Fonction urinaire; Incontinence; Multiple sclerosis; Sclérose en plaques; Urinary function.

MeSH terms

Humans
Multiple Sclerosis* / complications
Multiple Sclerosis* / epidemiology
Prevalence
Retrospective Studies
Urinary Bladder, Neurogenic* / complications
Urinary Bladder, Neurogenic* / epidemiology
Urinary Bladder, Overactive* / epidemiology