The association of diet and depression: an analysis of dietary measures in depressed, non-depressed, and healthy youth

Nutr Neurosci. 2022 Sep;25(9):1948-1955. doi: 10.1080/1028415X.2021.1918981. Epub 2021 May 3.

Abstract

Background: The association of diet quality with depression among the pediatric age group has been inconsistent. This may be due, in part, to varying dietary assessment methods. The current study sought to examine this association, and its reliability, using four dietary measures previously studied in children and adolescents.

Methods: Dietary habits among 139 children and adolescents (10-18 years, 66% female) with major depressive disorder [MDD (n = 77)], non-MDD psychiatric conditions (PSYCH; n = 31), or without psychiatric illness (healthy controls [HC]; n = 31) were examined. Using self-reported dietary intake, diet quality was characterized using the Youth Healthy Eating Index (YHEI), Dietary Questionnaire (DQ), Health Behaviour of Teenagers (HBT), and the Healthy Eating Habits Scale (HEHS). Multivariate Analysis of Covariances examined the association between depression status and dietary habits across measures controlling for participant age.

Results: The multivariate effect was significant by diet measures, F (16, 256) = 1.9, p = .02, partial η2 = 0.12, with significant differences across groups on consumption of healthy dietary practices and minimal variability across measures. In subgroup analyses, MDD children had decreased consumption of healthy foods compared with PSYCH and HC children on three out of four measures. There was no difference in consumption of unhealthy foods across diagnostic groups.

Limitations: Cross-sectional design.

Conclusions: Children with MDD consume fewer healthy foods than non-MDD children, with little variation by dietary measure. Research examining the directionality of this association and specific dietary deficits among MDD youth is needed to elucidate potential preventative targets for intervention.

Keywords: Diet; children and adolescents; clinical research; depression; dietary patterns; mental health; mood disorders; obesity risk.

MeSH terms

  • Adolescent
  • Child
  • Cross-Sectional Studies
  • Depression / epidemiology
  • Depressive Disorder, Major* / epidemiology
  • Diet / psychology
  • Female
  • Humans
  • Male
  • Reproducibility of Results