Leg ulcer with long-term hydroxyurea use

Clin Case Rep. 2021 Feb 24;9(4):2487-2488. doi: 10.1002/ccr3.3991. eCollection 2021 Apr.

Abstract

Long-term use of hydroxyurea can cause leg ulcers which usually do not heal unless the drug is discontinued. Patients should be counseled regarding alternative lines of treatment like anagrelide and pegylated-interferon.

Keywords: essential thrombocytosis; hematology; hydroxyurea.