Fluorescent light energy combined with systemic isotretinoin: A 52-week follow-up evaluating efficacy and safety in treatment of moderate-severe acne

Antonio Russo; Maiken Mellergaard; Giovanni Pellacani; Steven Nisticò; Michael Canova Engelbrecht Nielsen

doi:10.1002/ccr3.3944

Fluorescent light energy combined with systemic isotretinoin: A 52-week follow-up evaluating efficacy and safety in treatment of moderate-severe acne

Clin Case Rep. 2021 Feb 20;9(4):2057-2068. doi: 10.1002/ccr3.3944. eCollection 2021 Apr.

Authors

Antonio Russo¹, Maiken Mellergaard^{2

3}, Giovanni Pellacani⁴, Steven Nisticò⁵, Michael Canova Engelbrecht Nielsen^{3

6}

Affiliations

¹ Department of Medical Surgical and Neuro Sciences Dermatological Section University of Siena Siena Italy.
² Immunology Faculty of Health and Medical Sciences University of Copenhagen Frederiksberg C Denmark.
³ Klox Technologies Europe Dublin Ireland.
⁴ Department of Dermatology University of Modena and Reggio Emilia Modena Italy.
⁵ Department of Health Sciences, Unit of Dermatology Magna Graecia University Catanzaro Italy.
⁶ Klox R&D Center Guangdong Klox Biomedical Group Co., Ltd Guangzhou China.

Abstract

Fluorescent light energy therapy combined with low-dose isotretinoin or tetracycline show remarkable clinical effect on 12 cases of moderate-to-severe acne. Treatment was considered safe, well-tolerated, and highly efficacious.

Keywords: acne; combination therapy; fluorescent light energy; inflammation; isotretinoin; photobiomodulation.

Publication types

Case Reports