Favism-induced methemoglobinemia in a G6PD deficient male with a subsequent hemolytic cascade, a therapeutic challenge: Case report and review of literature

Fateen Ata; Saad Javed; Bassam Muthanna; Ines Dakhlia; Ammara Bint I Bilal; Motwakil Musa; Mashuk Uddin; Mohamed A Yassin

doi:10.1002/ccr3.3941

Favism-induced methemoglobinemia in a G6PD deficient male with a subsequent hemolytic cascade, a therapeutic challenge: Case report and review of literature

Clin Case Rep. 2021 Feb 20;9(4):2048-2052. doi: 10.1002/ccr3.3941. eCollection 2021 Apr.

Authors

Fateen Ata¹, Saad Javed², Bassam Muthanna¹, Ines Dakhlia¹, Ammara Bint I Bilal³, Motwakil Musa¹, Mashuk Uddin¹, Mohamed A Yassin⁴

Affiliations

¹ Department of Internal Medicine Hamad Medical Corporation Doha Qatar.
² Department of Internal Medicine Jinnah Hospital Allama Iqbal Medical College Lahore Pakistan.
³ Department of Radiology Hamad Medical Corporation Doha Qatar.
⁴ Department of Hematology National Center for Cancer Care & Research Hamad Medical Corporation Doha Qatar.

Abstract

The co-occurrence of acute hemolysis and methemoglobinemia secondary to favism in G6PD deficient individuals is rare. Identifying it promptly is of high clinical significance as treating methemoglobinemia (with methylene blue) can worsen hemolysis.

Keywords: Favism; G6PD; Hemolysis; fava beans; glucose‐6‐phosphate dehydrogenase; methemoglobinemia.

Publication types

Case Reports