Therapeutic efficiency of the APAF-1 antagonist LPT99 in a rat model of cisplatin-induced hearing loss

Clin Transl Med. 2021 Apr;11(4):e363. doi: 10.1002/ctm2.363.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Apoptosis / drug effects
  • Apoptotic Protease-Activating Factor 1 / antagonists & inhibitors*
  • Cells, Cultured
  • Cisplatin / adverse effects*
  • Cochlea / drug effects
  • Cochlea / ultrastructure
  • Disease Models, Animal
  • Hearing Loss / chemically induced*
  • Hearing Loss / drug therapy
  • Rats

Substances

  • Apaf1 protein, rat
  • Apoptotic Protease-Activating Factor 1
  • Cisplatin