Prevalence and associated factors of depressive symptoms among people living with HIV on antiretroviral therapy in Jakarta, Indonesia

Trop Med Int Health. 2021 Aug;26(8):908-915. doi: 10.1111/tmi.13597. Epub 2021 May 16.

Abstract

Objective: We aimed to investigate the prevalence of depressive symptoms among people living with HIV (PLHIV) on antiretroviral therapy (ART) in a large HIV treatment facility in Jakarta, Indonesia, and to assess associated factors.

Methods: The Indonesian version of Beck Depression Inventory-II was used to assess depressive symptoms of 346 participants visiting the HIV Integrated Clinic Cipto Mangunkusumo hospital between June and November 2018.

Results: Depressive symptoms (BDI-II score ≥14) were exhibited by 50.9% of participants, with prevalences of mild, moderate and severe depression of 30.4%, 15.6% and 4.9%, respectively. Poisson regression with robust variance analysis indicated that having lower income (aPR = 1.38, 95% CI 1.12-1.63), duration of ART for 1-5 years (aPR = 1.25, 95% CI 1.01-1.54) and same-sex partnership (aPR = 1.27, 95% CI 1.02-1.58) were positively associated with depressive symptoms. Age, sex and history of using intravenous drugs, and ART-based regimen were not associated with depressive symptoms.

Conclusions: Depressive symptoms were common among our population despite long-term ART use and were associated with having low-income, ART for 1-5 years and same-sex partnership.

Keywords: antiretroviral therapy; depression; depressive symptoms; human immunodeficiency virus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antiretroviral Therapy, Highly Active*
  • Cross-Sectional Studies
  • Depressive Disorder / epidemiology*
  • Depressive Disorder / etiology
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / psychology
  • Humans
  • Indonesia / epidemiology
  • Male
  • Prevalence
  • Psychometrics
  • Risk Factors