Electrochemical Detection of Glucose Molecules Using Laser-Induced Graphene Sensors: A Review

Sensors (Basel). 2021 Apr 16;21(8):2818. doi: 10.3390/s21082818.

Abstract

This paper deals with recent progress in the use of laser-induced graphene sensors for the electrochemical detection of glucose molecules. The exponential increase in the exploitation of the laser induction technique to generate porous graphene from polymeric and other naturally occurring materials has provided a podium for researchers to fabricate flexible sensors with high dynamicity. These sensors have been employed largely for electrochemical applications due to their distinct advantages like high customization in their structural dimensions, enhanced characteristics and easy roll-to-roll production. These laser-induced graphene (LIG)-based sensors have been employed for a wide range of sensorial applications, including detection of ions at varying concentrations. Among the many pivotal electrochemical uses in the biomedical sector, the use of these prototypes to monitor the concentration of glucose molecules is constantly increasing due to the essentiality of the presence of these molecules at specific concentrations in the human body. This paper shows a categorical classification of the various uses of these sensors based on the type of materials involved in the fabrication of sensors. The first category constitutes examples where the electrodes have been functionalized with various forms of copper and other types of metallic nanomaterials. The second category includes other miscellaneous forms where the use of both pure and composite forms of LIG-based sensors has been shown. Finally, the paper concludes with some of the possible measures that can be taken to enhance the use of this technique to generate optimized sensing prototypes for a wider range of applications.

Keywords: copper; glucose; laser-induced graphene; nanomaterials; sensors.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Electrochemical Techniques
  • Glucose
  • Graphite*
  • Humans
  • Lasers

Substances

  • Graphite
  • Glucose