Polyphenols Rich Diets and Risk of Type 2 Diabetes

Nutrients. 2021 Apr 24;13(5):1445. doi: 10.3390/nu13051445.

Abstract

Type 2 diabetes is an increasing health concern worldwide. Both genetic and environmental risk factors as improper dietary habits or physical inactivity are known to be crucial in the pathogenesis of type 2 diabetes. Polyphenols are a group of plant-derived compounds with anti-inflammatory and antioxidant properties that are associated with a low prevalence of metabolic conditions characterized by insulin resistance, including obesity, diabetes, and hypertension. Moreover, there is now full awareness that foods that are rich in phytochemicals and polyphenols could play an important role in preserving human cardiovascular health and substantial clinical evidence indicates that regular dietary consumption of such foods affects favorably carbohydrate metabolism. This review briefly summarizes the evidence relating dietary patterns rich in polyphenols with glucose metabolism and highlights the potential benefits of these compounds in the prevention of type 2 diabetes.

Keywords: diabetes; diet; dietary patterns; polyphenols.

Publication types

  • Review

MeSH terms

  • Anthocyanins / therapeutic use*
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Diet / methods*
  • Flavonoids / therapeutic use*
  • Humans

Substances

  • Anthocyanins
  • Flavonoids
  • flavan-3-ol