Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania

Healthcare (Basel). 2021 Apr 1;9(4):383. doi: 10.3390/healthcare9040383.

Abstract

Breast cancer is the most common cause of mortality due to cancer for women both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis. Extended term periods are required to estimate survival of, e.g., 15-20 years. Moreover, since mortality of the average population changes with time, estimates of survival of cancer patients derived after a long period of observation can become outdated and can be no longer used to estimate survival of patients who were diagnosed later. Therefore, it can be useful to construct analytic functions that describe survival probabilities. Shorter periods of observation can be enough for such construction. We used the data collected by the Lithuanian Cancer Registry for our analysis. We estimated the chances of survival for up to 5 years after patients were diagnosed with breast cancer in Lithuania. Then we found analytic survival functions which best fit the observed data. At the end of this paper, we provided some examples for applications and directions for further research. We used mainly the Kaplan-Meier method for our study.

Keywords: Kaplan–Meier estimate; breast cancer; cancer awareness campaign; central death rate; exposed to risk; survival analysis.