Mesenchymal stem cells (MSCs) are pluripotent stem cells with high self-proliferation and multidirectional differentiation potential. They also have other functions including immune regulation, paracrine and so on, playing an important role in repairing injured tissues. In recent years, a lot of research has been done on how MSCs promote skin injury repair, and a lot of progress has been made. Compared with direct injection of MSCs in the wound area, some special treatments or transplantation methods could enhance the ability of MSCs to repair skin injury. This paper mainly discusses the role of MSCs in skin injury repair and technical ways to improve its repairing capacity, and discusses the existing problems in this field and prospects for future research directions.
间充质干细胞（MSCs）是一种可高度自我增殖和具有多向分化潜能的多能干细胞，其自身还具有免疫调节、旁分泌等功能，在机体损伤组织的修复中扮演了重要角色。近年来，人们在 MSCs 促进皮肤损伤修复方面做了大量研究，取得了较多的进展，并且发现比起在伤口区域直接注射 MSCs，可以对其进行一些特殊处理或改进移植方式来提高修复皮肤损伤的能力。本文主要就 MSCs 在皮肤损伤修复中的作用和提高其修复能力的相关技术手段两个方面进行阐述，并探讨了该研究领域存在的问题和展望了未来的研究方向。.
Keywords: cell transplantation; mesenchymal stem cells; repairing efficiency; skin injury; tissue repair.