[Kidney transplantation in the elderly: A benefit for all patients?]

Nephrol Ther. 2021 Apr:17S:S115-S118. doi: 10.1016/j.nephro.2020.02.007.
[Article in French]

Abstract

Age per se should not be a contraindication to kidney transplantation. The first studies have shown a benefit for the survival of elderly eligible patients getting a kidney transplant compared to be maintained on the waiting list. However, more recent data suggest that this benefit is not as constant, notably with a significant early mortality period. The eligibility of elderly patients for transplantation must be based on the usual consideration of co-morbidities, but should also include, for some patients, a geriatric evaluation to detect clinical symptoms of frailty. The decision to transplant an elderly recipient must also integrate the characteristics of the donors, since the use of donors with increasingly expanding criteria can have a negative impact on the survival of these patients.

Keywords: Elderly; Fragilité; Frailty; Kidney transplantation; Mortality; Mortalité; Sujet âgé; Transplantation rénale.

MeSH terms

  • Aged
  • Comorbidity
  • Humans
  • Kidney Transplantation*
  • Tissue Donors
  • Waiting Lists