Comparison between thulium laser vapoenucleation and plasmakinetic resection of the prostate in men aged 75 years and older in a real-life setting: a propensity score analysis

Aging Clin Exp Res. 2021 Jun;33(6):1757-1763. doi: 10.1007/s40520-021-01868-1. Epub 2021 Apr 28.

Abstract

Background: Urologists may hesitate to offer transurethral resection of the prostate (TURP) because of increased morbidity in elderly patients.

Aims: We aimed to compare data on postoperative outcomes of elderly men undergoing bipolar transurethral resection of the prostate (B-TURP) as compared to thulium laser vapoenucleation of the prostate (ThuVEP).

Methods: We retrospectively reviewed data of all patients aged ≥ 75 years who underwent benign prostatic hyperplasia surgery. Differences between interventions were estimated using propensity scores (PS) to adjust for different patients characteristics.

Results: Between 2017 and 2020, 275 men were included in the analysis. Propensity score retrieved 65 patients in each group. Median age was 78 (4) years in B-TURP group and 78 (6) in ThuVEP group. Median prostate volume was 63 (35) ml and 54 (24) ml in B-TURP group and ThuVEP group, respectively. Only American Society of Anesthesiologists score was significantly higher in ThuVEP group (p = 0.006). Median operation time, catheterization time, and hospital stay were similar in both groups (55 min, 2 and 3 days). Overall, 84.6% of men had no complications, with no significant differences between the groups (p = 0.234). Only one patient in B-TURP group experienced a Clavien grade IIIb complication. By 1 year, there were a statistically significant differences in International Prostate Symptom Score (p = 0.000) in favor of B-TURP group and in maximal urine flow rate (p = 0.000) in favor of ThuVEP group.

Discussion and conclusions: Both procedures showed excellent functional improvements one year after surgery with a low rate of major complications in men aged ≥ 75 years with small-to-medium sized prostates.

Keywords: Aging; Laser therapy; Plasmakinetic resection of the prostate; Thulium laser vapoenucleation of the prostate; Transurethral resection of prostate.

MeSH terms

  • Aged
  • Humans
  • Laser Therapy*
  • Lasers
  • Male
  • Propensity Score
  • Prostatic Hyperplasia* / surgery
  • Retrospective Studies
  • Thulium
  • Transurethral Resection of Prostate* / adverse effects
  • Treatment Outcome

Substances

  • Thulium