HLA-C*17 in COVID-19 patients: Hints for associations with severe clinical outcome and cardiovascular risk

Immunol Lett. 2021 Jun:234:44-46. doi: 10.1016/j.imlet.2021.04.007. Epub 2021 Apr 24.
No abstract available

Keywords: CD8+ cytotoxic T cells; COVID-19; Cardiovascular, SARS-CoV-2; HLA; KIR; Troponin-T.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • CD8-Positive T-Lymphocytes / immunology*
  • COVID-19 / diagnosis
  • COVID-19 / mortality
  • COVID-19 / pathology*
  • Cardiovascular Diseases / complications
  • Cardiovascular Diseases / pathology*
  • Cardiovascular Diseases / virology
  • Female
  • Genetic Predisposition to Disease / genetics
  • HLA-C Antigens / genetics*
  • HLA-C Antigens / immunology
  • Heart Disease Risk Factors
  • Humans
  • Lymphocyte Activation / immunology
  • Male
  • Middle Aged
  • Receptors, KIR / genetics
  • Receptors, KIR2DL1 / genetics
  • SARS-CoV-2 / immunology

Substances

  • HLA-C Antigens
  • HLA-C*17:01 antigen
  • KIR2DL1 protein, human
  • KIR2DS1 protein, human
  • Receptors, KIR
  • Receptors, KIR2DL1