Gender differences in the perception of asthma respiratory symptoms in five Latin American countries

J Asthma. 2022 May;59(5):1030-1040. doi: 10.1080/02770903.2021.1922914. Epub 2021 May 10.

Abstract

Objectives: To determine the differences between sexes in perceptions of asthma symptoms, asthma control, daily activities, and symptom exacerbation in Latin American countries.

Methods: This cross-sectional study was performed using data from the Latin America Asthma Insight and Management (LA-AIM) study (n = 2167) carried out in Argentina, Brazil, Mexico, Venezuela, and Puerto Rico. Face-to-face interviews were conducted, and patients orally completed a 53-question survey assessing five main domains of asthma: symptoms, impact on daily activities, disease control, exacerbation, and treatment/medication.

Results: Of the 2167 participants, 762 (35.2%) were males and 1405 (64.8%) were females. Male participants smoked more than females, but history of rhinitis and allergies was more common in females (p < 0.05). Women aged 18-40 years had a higher proportion of uncontrolled asthma compared to men of the same age (37.8% and 30.0%, respectively). A higher proportion of symptomatic females reported more frequent symptoms (daytime cough, shortness of breath, breathlessness/wheezing, sputum, tightness in the chest, etc.) than males (p < 0.05). Females also experienced more limitations in sports/recreational activities, normal physical exertion, social activities, sleep, and daily activities. Females consulted with health professionals more often than males (67.8% and 59.6%, respectively; p < 0.05). Asthma caused a feeling of lack of control over life in 42.6% of females and 31.4% of males.

Conclusion: In Latin America, females report more asthma symptoms, poorer asthma control, more impact on their daily activities, and more visits with health professionals than males.

Keywords: Latin America; activities of daily living; asthma; quality of life; sex; signs and symptoms.

MeSH terms

  • Asthma* / drug therapy
  • Asthma* / epidemiology
  • Cross-Sectional Studies
  • Dyspnea
  • Female
  • Humans
  • Latin America / epidemiology
  • Male
  • Perception
  • Sex Factors