Hyperpigmentation of an Atherosclerotic Carotid Artery Plaque in a Patient on Chronic Suppressive Minocycline Therapy

Ann Vasc Surg. 2021 Aug:75:533.e1-533.e4. doi: 10.1016/j.avsg.2021.03.043. Epub 2021 Apr 24.

Abstract

Minocycline is an oral tetracycline antibiotic that has been used to treat a variety of medical conditions. A recognized side effect of minocycline is hyperpigmentation, most commonly a cutaneous phenomenon affecting the lower extremities. In our case report, we present a patient on chronic suppressive minocycline therapy identified intraoperatively with hyperpigmentation involving an atherosclerotic carotid plaque.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Carotid Artery Diseases / complications*
  • Carotid Artery Diseases / diagnostic imaging
  • Carotid Artery Diseases / surgery
  • Drug Administration Schedule
  • Endarterectomy, Carotid
  • Humans
  • Hyperpigmentation / chemically induced*
  • Hyperpigmentation / diagnosis
  • Male
  • Minocycline / administration & dosage
  • Minocycline / adverse effects*
  • Plaque, Atherosclerotic*

Substances

  • Anti-Bacterial Agents
  • Minocycline