Movement Disorder Emergencies

Neurol Clin. 2021 May;39(2):615-630. doi: 10.1016/j.ncl.2021.01.005. Epub 2021 Mar 31.

Abstract

Acute presentation of new movement disorders and acute decompensation of chronic movement disorders are uncommon but potentially life-threatening. Inadvertent or purposeful overdose of many psychiatric medications can result in acute life-threatening movement disorders including serotonin syndrome, neuroleptic malignant syndrome, and malignant catatonia. Early withdrawal of potentiating medications, treatment with benzodiazepines and other diagnosis-specific drugs, and providing appropriate supportive care including airway and breathing management, hemodynamic stabilization, fluid resuscitation, and renal support including possible hemodialysis are the mainstays of acute management. Many of these conditions require admission to the neurologic intensive care unit.

Keywords: Dystonia; Encephalopathy; Hyperpyrexia; Malignant catatonia; Neuroleptic malignant syndrome; Parkinson disease; Psychosis; Serotonin syndrome.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acute Disease
  • Adolescent
  • Aged
  • Emergencies
  • Female
  • Humans
  • Male
  • Movement Disorders / diagnosis*
  • Movement Disorders / therapy*