Malignant Peripheral Nerve Sheath Tumour in a Seba's Short-Tailed Bat (Carollia perspicillata)

Jan Franzen; Sara Soto; Nicolas J Fasel; Peggy Rüegg-van den Broek; Inês B Veiga

doi:10.1016/j.jcpa.2021.02.004

Malignant Peripheral Nerve Sheath Tumour in a Seba's Short-Tailed Bat (Carollia perspicillata)

J Comp Pathol. 2021 Apr:184:72-76. doi: 10.1016/j.jcpa.2021.02.004. Epub 2021 Mar 25.

Authors

Jan Franzen¹, Sara Soto², Nicolas J Fasel³, Peggy Rüegg-van den Broek⁴, Inês B Veiga²

Affiliations

¹ Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland. Electronic address: jan.franzen@vetsuisse.unibe.ch.
² Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
³ Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.
⁴ Foundation Papiliorama, Kerzers, Switzerland.

PMID: 33894882
DOI: 10.1016/j.jcpa.2021.02.004

Abstract

There are few reports of tumours in bats, despite the fact that members of the Chiroptera order include 22.4% of all currently known mammal species. We now describe a case of malignant peripheral nerve sheath tumour (MPNST) in an adult female Seba's short-tailed bat (Carollia perspicillata) from a private zoo in Switzerland. The macroscopical and histological findings indicated that the MPNST originated from a dorsal spinal nerve root sheath in the lumbar region and metastasized to the spleen. Immunohistochemical labelling for glial fibrillary acid protein, S100 protein, neuron specific enolase and synaptophysin was negative. The cytoplasm of a few neoplastic cells labelled for smooth muscle actin and desmin. To our knowledge, this is the first report of a PNST in a member of the Chiroptera order.

Keywords: Seba's short-tailed bat; malignant peripheral nerve sheath tumour.

Publication types

Case Reports

MeSH terms

Animals
Animals, Zoo
Chiroptera*
Female
Neurofibrosarcoma* / veterinary
Switzerland