Exposure to PM2.5 Enhances the PI3K/AKT Signaling and Malignancy of ERα Expression-dependent Non-small Cell Lung Carcinoma

Biomed Environ Sci. 2021 Apr 20;34(4):319-323. doi: 10.3967/bes2021.041.

Authors

Lei Tian¹, Ying Li², Huan Liang Liu¹, Wen Qing Lai¹, Yue Shi¹, Xiao Hua Liu¹, Zhu Ge Xi¹, Ben Cheng Lin¹

Affiliations

¹ Tianjin Institute of Environmental and Operational Medicine, Tianjin 300050, China.
² The Third Surgical Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300070, China.

PMID: 33894812
DOI: 10.3967/bes2021.041

No abstract available

Publication types

Letter

MeSH terms

Air Pollutants / toxicity*
Carcinoma, Non-Small-Cell Lung / genetics
Carcinoma, Non-Small-Cell Lung / metabolism*
Carcinoma, Non-Small-Cell Lung / pathology
Cell Line, Tumor
Cell Proliferation / drug effects
Estrogen Receptor alpha / genetics
Estrogen Receptor alpha / metabolism*
Humans
Lung Neoplasms / genetics
Lung Neoplasms / metabolism*
Lung Neoplasms / pathology
Neoplasm Invasiveness
Particulate Matter / toxicity*
Phosphatidylinositol 3-Kinases / metabolism*
Proto-Oncogene Proteins c-akt / metabolism*
Signal Transduction / drug effects

Substances

Air Pollutants
ESR1 protein, human
Estrogen Receptor alpha
Particulate Matter
Proto-Oncogene Proteins c-akt